Status:
COMPLETED
Freezing of Gait in Parkinson's Disease
Lead Sponsor:
Duke University
Conditions:
Parkinson Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study is designed to evaluate whether a specific visuospatial training task will change gait performance of Parkinson's disease (PD) patients in doorways, specifically freezing of gait.
Detailed Description
This study is a randomized, prospective, single-blinded six-week study in PD patients with freezing of gait (FOG). This study will involve 2 study groups: Group A - training group; Group B - no trai...
Eligibility Criteria
Inclusion
- Age: greater than 18 years old and without an upper age limit
- diagnosis of idiopathic PD exhibiting at least 2 or 3 cardinal signs (bradykinesia, rigidity, and resting tremor)
- Ambulate independently without an assistive device for at least 60 meters
- Freezing of gait episodes confirmed through the FOG-Q and evaluation by a fellowship trained Movement Disorder neurologist
- Willingness and ability to participate in training and complete training diary
- Documented FOG-Q and Unified Parkinson's Disease Rating Scale (UPDRS) II
- Ability to sign informed consent
- Pregnant females will be included in the study and there are no known risks to the pregnant female or fetus
Exclusion
- Inability to complete questionnaires
- Unwillingness to participate in training, complete all questionnaires and training diary
- Subjects with secondary causes of parkinsonism
- Significant dementia (MOCA \<20)
- Prior deep brain stimulation (DBS) surgery or pallidotomy
- Subjects cannot participate in any form of Physical Therapy, Occupational Therapy or Speech Therapy during the study period
- Subjects cannot start any new medications during the study period.
Key Trial Info
Start Date :
June 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2014
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01887054
Start Date
June 1 2013
End Date
August 1 2014
Last Update
January 24 2017
Active Locations (1)
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1
Duke University Medical Center
Durham, North Carolina, United States, 27705