Status:

TERMINATED

Cardiac Allograft Remodeling and Effects of Sirolimus

Lead Sponsor:

University of Nebraska

Conditions:

Cardiac Hypertrophy

Immunosuppression

Eligibility:

All Genders

19-70 years

Phase:

PHASE1

Brief Summary

Cardiac allograft remodeling causes poor quality of life, allograft failure and increased mortality after heart transplantation. Risk factors for cardiac allograft remodeling and its progression are p...

Detailed Description

Heart transplantation has become a well-established treatment option for patients with end-stage heart disease and currently has a one-year survival rate of 90%, a five-year survival rate of 70%, and ...

Eligibility Criteria

Inclusion

  • All adult cardiac transplant recipients undergoing heart transplantation at UNMC/TNMC.

Exclusion

  • Adult cardiac transplant recipients with acute rejection (ISHLT R\> grade 2) or acute infection.

Key Trial Info

Start Date :

April 24 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 27 2018

Estimated Enrollment :

42 Patients enrolled

Trial Details

Trial ID

NCT01889992

Start Date

April 24 2013

End Date

September 27 2018

Last Update

August 30 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Nebraska Medical Center

Omaha, Nebraska, United States, 68198