Status:
UNKNOWN
Acupoint Electric Stimulation Combined With Tropisetron in Preventing and Treating Nausea and Vomiting After TACE
Lead Sponsor:
Fudan University
Conditions:
Nausea
Vomiting
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
Observation on acupoint electric stimulation combined with tropisetron in preventing and treating nausea and vomiting and improving the patient's appetite after TACE for primary or metastatic liver ca...
Detailed Description
* Classification of nausea and vomiting, as measured by NCI CTC-AE version 3 * The improvement of appetite, as measure by the classification of Appetite in accordance with NCI CTC-AE version 3. * Qual...
Eligibility Criteria
Inclusion
- ECOG physical status 0,1,2
- would accept the transcatheter hepatic arterial chemoembolization of primary or metastatic liver cancer patients;
- Adult male and female 3, age 18 years old;
- the chem-scheme of arterial infusion chemotherapy based on oxaliplatin dosage of 200mg;
- signed the informed consent and understand the study design;
- Organ function examination in patients must meet the following laboratory indexes: Neutrophil\>500/Ul, hemoglobin \> 8 gm/dL, platelet \>100000/uL,Creatinine \< 2 mg/dL bilirubin \< 1.5 mg/dL, , alanine aminotransferase \< 3 times the normal value, albumin \>30g/L
- understand and complete quality of life scale ;
- women of childbearing age urine pregnancy test was negative.
Exclusion
- The combined use of other venous chemotherapy within 5 days after TACE;
- skin infection on or near the points;
- skin hyperalgesia, unable to withstand electrical stimulation;
- other confounding factors may cause nausea and vomiting (such as intestinal obstruction, anorexia, etc.);
- heart, cerebrovascular accident history or the history of spinal cord injury;
- intestinal obstruction lead to nausea and vomiting
- installing pacemaker;
- cognitive dysfunction, unable to finish Scale;
- currently using acupuncture therapy.
Key Trial Info
Start Date :
June 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2014
Estimated Enrollment :
74 Patients enrolled
Trial Details
Trial ID
NCT01895010
Start Date
June 1 2013
End Date
December 1 2014
Last Update
July 10 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Shanghai Cancer Center
Shanghai, Shanghai Municipality, China, 200032