Status:

COMPLETED

The Influence of Aerobic Exercise on Cognitive Functioning in Schizophrenia.

Lead Sponsor:

New York State Psychiatric Institute

Collaborating Sponsors:

National Institute of Mental Health (NIMH)

Conditions:

Schizophrenia

Eligibility:

All Genders

18-55 years

Phase:

NA

Brief Summary

The aim of this study is to look at the effects of Aerobic Exercise (AE) on daily and neurocognitive functioning including memory, attention, the ability to plan activities, and learn new information....

Detailed Description

Individuals with schizophrenia often display cognitive difficulties. Studies among non-clinical populations suggest that Aerobic Exercise (AE) training is effective in increasing both aerobic fitness ...

Eligibility Criteria

Inclusion

  • Males and females between ages 18-55.
  • Have capacity to give informed consent.
  • English speaking.
  • Have a DSM-IV diagnosis of schizophrenia.
  • Taking antipsychotic medication for at least 8 weeks and on current doses for 4 weeks, and/or injectable depot antipsychotics with no change in last 3 months.
  • Medically cleared to exercise.

Exclusion

  • Lacks capacity to give informed consent.
  • Have used street drugs within the past 4 weeks.
  • Have history of of hypertension of cardiac conditions.
  • Have history of active suicidal ideation or serious self-destructive behavior.
  • Have history of violence or aggressive behavior.
  • Have history of neurological or medical conditions known to seriously affect the brain.
  • Pregnant or nursing.
  • Completing more than 2 hours of moderate or higher levels of aerobic exercise per week.
  • Participation in a study of cognition during the previous 2 months.

Key Trial Info

Start Date :

April 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2014

Estimated Enrollment :

41 Patients enrolled

Trial Details

Trial ID

NCT01897064

Start Date

April 1 2012

End Date

July 1 2014

Last Update

August 15 2014

Active Locations (1)

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Columbia University & New York State Psyciatric Institute

New York, New York, United States, 10032