Status:
COMPLETED
Ischemic Postconditioning on Microvascular Obstruction in Reperfused Myocardial Infarction
Lead Sponsor:
Fundación para la Investigación del Hospital Clínico de Valencia
Collaborating Sponsors:
Instituto de Salud Carlos III
Conditions:
Myocardial Infarction
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Objectives. We will evaluate the effect of ischemic postconditioning (PCON) on microvascular obstruction (MVO) in patients with a first ST-segment elevation myocardial infarction (STEMI) treated with ...
Detailed Description
INTRODUCTION In ST-segment elevation myocardial infarction (STEMI) timely coronary reperfusion is the primary therapeutic goal to improve patients' outcome and to reduce left ventricular (LV) infarct...
Eligibility Criteria
Inclusion
- Patients of age ≥ 18 years admitted to two university hospitals for a first STEMI within the first 12 h of chest pain onset, with ST-segment elevation of \>0.1 mV in at least 2 contiguous leads and for whom the clinical decision to treat with percutaneous coronary intervention is made.
Exclusion
- Documented history of previous infarction
- Primary percutaneous revascularization not attempted
- Severe clinical or hemodynamic deterioration
- Left main stem disease
- Thrombolysis In Myocardial Infarction (TIMI) 2-3
- Rentrop collateral flow grade ≥1 upon patient arrival
- Death, re-infarction, cardiac surgery or severe clinical deterioration before CMR study
- Patients who denied participation in the registry
- Any contraindications to CMR
Key Trial Info
Start Date :
October 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2012
Estimated Enrollment :
243 Patients enrolled
Trial Details
Trial ID
NCT01898546
Start Date
October 1 2011
End Date
July 1 2012
Last Update
July 12 2013
Active Locations (1)
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1
Cardiology Department. Hospital Clinico Universitario-INCLIVA. University of Valencia.
Valencia, Valencia, Spain, 46010