Status:

COMPLETED

A Simple Clinical Tool to Help Diagnose Pulmonary Embolism: Phase 1

Lead Sponsor:

Mayo Clinic

Conditions:

Pulmonary Embolism

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The goal of this project is to determine if the change in oxygen saturation during deep inspiration ("augmented pulse oximetry") can be used as a method to rule out pulmonary embolism (PE). The invest...

Detailed Description

Patients will be identified and enrolled by the Mayo Clinic St. Marys Emergency Department staff as they are undergoing medical care in the Emergency Department. The investigators will calculate the ...

Eligibility Criteria

Inclusion

  • 18 years of age or greater.
  • Agrees and able to participate in the study.
  • Room air SpO2 (oxygen saturation) less than 92% and newly-diagnosed PE (or controls with no PE) based on CT angiogram result.

Exclusion

  • Clinical concern for instability.
  • Systolic blood pressure less than 100 mm Hg.
  • Heart rate ≥140 beats per minute.
  • Oxygen saturation less than 85% with more than 4 L supplemental oxygen.
  • Unable to participate/comply with instructions for using the incentive spirometer.
  • Patients from the Federal Medical Center in Rochester, Minnesota.
  • Patients who do not speak English (due to the need for expediency).
  • Patients will be under the care of the Emergency Department team who have the skills and resources to monitor and treat patients if they were to become unstable.

Key Trial Info

Start Date :

June 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 11 2024

Estimated Enrollment :

64 Patients enrolled

Trial Details

Trial ID

NCT01898637

Start Date

June 1 2013

End Date

November 11 2024

Last Update

March 28 2025

Active Locations (1)

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Mayo Clinic

Rochester, Minnesota, United States, 55905