Status:
COMPLETED
Surgery in Chronic Cough GERD Related
Lead Sponsor:
University of Bologna
Conditions:
GERD
Eligibility:
All Genders
18+ years
Brief Summary
The effectiveness of surgical fundoplication in treating classical reflux symptoms is well documented, but the role of surgery in alleviating extra-esophageal symptoms allegedly secondary to gastro-es...
Detailed Description
Pre-operatively, patients routinely underwent the symptoms assessment, barium swallow, upper gastro-intestinal endoscopy and esophageal manometry. The type and severity of symptoms and the grade of r...
Eligibility Criteria
Inclusion
- patients aged \> 18 years, affected by chronic cough (\> 8 weeks)associated with GERD typical symptoms, negative for pulmonary diseases on chest HRCT scan, on methacholine challenge test and spirometry, undergoing anti-reflux surgery
Exclusion
- patients with chronic cough (\> 8 weeks) positive for pulmonary diseases on chest High Resolution Computed Tomography (HRCT) scan, methacholine challenge test and spirometry; association of GERD with epiphrenic esophageal diverticulum, collagen diseases, undetermined esophageal motility disorders, redo antireflux surgery, previous surgery on the thoracic and abdominal esophagus and stomach,on the diaphragm.
Key Trial Info
Start Date :
January 1 1995
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2012
Estimated Enrollment :
67 Patients enrolled
Trial Details
Trial ID
NCT01899183
Start Date
January 1 1995
End Date
January 1 2012
Last Update
July 15 2013
Active Locations (1)
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1
Department of Medical And Surgical Sciences University of Bologna
Bologna, BO, Italy, 40138