Status:
UNKNOWN
Blood Pressure Response to Sodium in the Diet
Lead Sponsor:
University of Virginia
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Hypertension
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Previous studies have demonstrated that single nucleotide polymorphisms (SNPs) of the sodium-bicarbonate co-transporter gene (SLC4A5) are associated with hypertension. We tested the hypothesis that SN...
Detailed Description
Subjects are placed on an isocaloric diet, one week with high sodium(300mEq) and one week with low sodium(10mEq), in randomized order. Twenty-four hour urine sodium and urine creatinine levels verify ...
Eligibility Criteria
Inclusion
- Ages 18-70 (inclusive)
- Sex Male and female
- Race Caucasian and African-American/black
- BMI 18.-0-29.9
- BP Normal
Exclusion
- hypertension
- blood pressure \> 140/90 mmHg
Key Trial Info
Start Date :
January 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2021
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT01899495
Start Date
January 1 2005
End Date
August 1 2021
Last Update
October 18 2016
Active Locations (1)
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1
University of Virginia
Charlottesville, Virginia, United States, 22903