Status:
COMPLETED
Investigations of Mechanisms and Treatment in Post-traumatic Joint Contractures
Lead Sponsor:
University of Calgary
Collaborating Sponsors:
Canadian Institutes of Health Research (CIHR)
American Society for Surgery of the Hand
Conditions:
Joint Contractures
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
Injured joints, especially at the elbow, are at risk for permanent motion loss, also known as joint contractures. Joint contractures limit the function of an elbow and are a recognized complication th...
Detailed Description
Individuals ≥ 18 years old with isolated distal 1/3 humerus and/or proximal 1/3 ulna and/or proximal 1/3 radius fractures and/or elbow dislocations (open fractures with or without nerve injury may be ...
Eligibility Criteria
Inclusion
- Age ≥ 18 years old
- Isolated distal 1/3 humerus fractures
- Proximal 1/3 ulna fractures
- Proximal 1/3 radial fractures
- Elbow dislocations
- Open fractures with or without nerve injury
- Presentation to Peter Lougheed Centre (PLC), Foothills Medical Centre (FMC) or South Health Campus (SHC).
Exclusion
- Pre-existing elbow contracture
- Osteoarthritis of affected elbow
- Inflammatory arthritis of affected elbow
- Gout of affected elbow
- Nonspecific monoarticular arthritis of the affected elbow
- Inability to give informed consent due to irreversible cognitive disorder
- Inability to comply with post-operative physiotherapy
- Injury \> 7 days at the time of presentation
- Inability to mobilize elbow injury within 2 weeks of injury or surgery
- Pregnancy
- Breast feeding
- Oral hypoglycemic medications
- History of epilepsy
- Lactose intolerance
Key Trial Info
Start Date :
June 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2017
Estimated Enrollment :
152 Patients enrolled
Trial Details
Trial ID
NCT01902017
Start Date
June 1 2013
End Date
August 1 2017
Last Update
March 27 2018
Active Locations (3)
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1
Peter Lougheed Centre
Calgary, Alberta, Canada, T1Y 6J4
2
Foothills Medical Centre
Calgary, Alberta, Canada, T2N 1N4
3
South Health Campus
Calgary, Alberta, Canada