Status:
COMPLETED
Multiple Daily Doses of Aspirin to Overcome Hyporesponsiveness Post Cardiac Bypass Surgery (ASACABG)- Part B
Lead Sponsor:
Hamilton Health Sciences Corporation
Conditions:
Postoperative Dysfunction Following Cardiac Surgery
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
Cardiac bypass surgery is an important treatment for patients with severely blocked arteries (tubes that delivery oxygen and nutrients to the heart). Hundreds of thousands of these operations are done...
Detailed Description
Background: Cardiovascular disease caused by athero-thrombosis is the number one cause of long-term morbidity and death worldwide. Many patients with advanced coronary disease benefit from Coronary A...
Eligibility Criteria
Inclusion
- Adult subjects who undergo elective or urgent CABG surgery who are on or off aspirin during the preoperative period with or without valve replacement
Exclusion
- initial platelet count \<100,000
- receiving NSAIDs or other drugs that might interfere with aspirin's platelet-inhibitory effect
- clinically important bleeding (chest tube drainage \>200ml/hr for 6hrs), or bleeding disorders that preclude the use of randomized therapies
- patients who do not provide informed written consent
Key Trial Info
Start Date :
July 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2014
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT01902498
Start Date
July 1 2013
End Date
July 1 2014
Last Update
March 19 2015
Active Locations (1)
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1
Hamilton General Hospital
Hamilton, Ontario, Canada, L8L2X2