Status:

COMPLETED

Transient Elastography in Autoimmune Hepatitis

Lead Sponsor:

Universitätsklinikum Hamburg-Eppendorf

Conditions:

Liver Cirrhosis

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

Recent, research has focused on the evaluation of non-invasive methods for the assessment of liver fibrosis in patients with chronic liver disease. Among these methods, transient elastography is the m...

Detailed Description

The aim of the current study was to assess the diagnostic performance of transient elastography for the determination of cirrhosis in patients with autoimmune hepatitis compared to the diagnosis of ci...

Eligibility Criteria

Inclusion

  • Confirmed diagnosis of AIH based on the diagnostic criteria revised by the International Autoimmune Hepatitis Group 2008 (20):
  • liver related autoantibodies,
  • hypergammaglobulinaemia,
  • typical histological findings and
  • absence of viral markers.

Exclusion

  • morbid obesity (BMI \> 40),
  • ascites, ileus or subileus,
  • peritonitis,
  • pregnancy,
  • extrahepatic cholestasis and
  • a severe inflammatory flare of AIH.

Key Trial Info

Start Date :

August 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2013

Estimated Enrollment :

34 Patients enrolled

Trial Details

Trial ID

NCT01905254

Start Date

August 1 2007

End Date

January 1 2013

Last Update

May 6 2015

Active Locations (1)

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Dept of Gastroenterology and Hepatology, University Medical Center Hamburg Eppendorf

Hamburg, Hamburg, Germany, 20246