Status:
COMPLETED
Elevated FFA and Skeletal Muscle Lipid Content
Lead Sponsor:
Maastricht University Medical Center
Conditions:
Diabetes
Exercise Physiology
Eligibility:
MALE
18-30 years
Phase:
NA
Brief Summary
There is increasing evidence that skeletal muscle lipid content (IntraMyoCellular Lipid, IMCL) markedly increases the risk of metabolic complications, including insulin resistance and cardiovascular e...
Eligibility Criteria
Inclusion
- Male sex
- Age 18-30 years
- Lean, BMI 18-25 kg/m2
- Healthy
- Stable dietary habits
- No medication use
Exclusion
- Female sex
- Engagement in programmed exercise \> 2 hours total per week
- Cardiac problems, such as angina pectoris, cardiac infarction and arrhythmias
- First degree relatives with type 2 diabetes mellitus
- Any medical condition requiring treatment and/or medication use
- Unstable body weight (weight gain or loss \> 3 kg in the past three months)
- Participation in other biomedical study within 1 month prior to the screening visit
- Subjetcs, who do not want to be informed about unexpected medical findings, or do not wish that their treating physician is informed, cannot participate in the study
Key Trial Info
Start Date :
May 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2013
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT01906333
Start Date
May 1 2013
End Date
August 1 2013
Last Update
May 28 2015
Active Locations (1)
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1
Department of Human Biology, Maastricht University Medical Center (MUMC)
Maastricht, Netherlands