Status:
COMPLETED
Respiratory Physiology in Children With Febrile Seizures.
Lead Sponsor:
Charite University, Berlin, Germany
Collaborating Sponsors:
Sana-Klinikum Lichtenberg
Conditions:
Febrile Illness Acute
Seizures, Febrile
Eligibility:
All Genders
3-5 years
Brief Summary
Febrile seizures occur in 2-5% of the population and are typically limited to children between 3 months and 5 years-of-age. The pathophysiological link between increased body temperature and increased...
Detailed Description
The aim of the study is the continuous non-invasive monitoring of * body temperature * respiratory rate * transcutaneous pCO2 * heart rate * pulsoxymetric SaO2 (arterial oxygen saturation) during a f...
Eligibility Criteria
Inclusion
- Febrile illness with body temperature ≥38.0 degree C
- 50% of study population: never had a febrile seizure
- 50% of study population: simple or complex febrile seizure within one day of investigation
- Change of body temperature of ≥1.0 degree C during the monitoring period
- Provision of written informed consent by the parents or guardians of the child
- Artefact-free simultaneous measurement of respiratory rate, pCO2 (transcutaneous probe), body temperature (rectal probe), and heart rate during change of body temperature of ≥1.0 degree C.
Exclusion
- Past history of afebrile seizures
- Past history of neonatal seizures
- Retarded psychomotor development
- Chronic respiratory disease
- Cardiologic disease
- Severe other organ disease
- Permanent medication for chronic disorder
- Therapeutic increase of inspiratory oxygen concentrations during the observational period
Key Trial Info
Start Date :
July 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2014
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT01906619
Start Date
July 1 2011
End Date
December 1 2014
Last Update
January 2 2026
Active Locations (1)
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1
Charité Universitätsmedizin Berlin
Berlin, Germany, 13353