Status:
COMPLETED
Prevention Trial of Family Focused Treatment in Youth at Risk for Psychosis
Lead Sponsor:
University of California, Los Angeles
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Psychosis
Eligibility:
All Genders
12-35 years
Phase:
NA
Brief Summary
Preventing psychotic disorders such as schizophrenia and associated functional disability could relieve an enormous burden of personal and family suffering and economic losses to society. This project...
Detailed Description
The goal of this research is to conduct a multisite randomized trial to determine the efficacy of a 6-month Family-Focused Treatment (FFT) in comparison with Enhanced Care (EC), a treatment-as-usual i...
Eligibility Criteria
Inclusion
- Age between 12 years, 0 months and 35 years, 11 months
- Speaks and writes English
- Availability of at least one family member for treatment
- Meets criteria for one of three prodromal syndromes as assessed by the
- Structured Interview for Prodromal Syndromes:
- attenuated positive symptoms that are sub-psychotic in duration and intensity and have begun or worsened in the past year;
- brief intermittent psychosis, defined as or syndromal psychotic symptoms that are have been present intermittently with onset in the previous 3 months; or
- genetic risk and deterioration, defined as a diagnosis of schizotypal personality disorder or having a first degree relative with a psychotic disorder, plus having experienced a substantial decline (30% or greater) in Global Assessment of Functioning scores in the last year.
Exclusion
- Diagnosis of schizophrenia or schizoaffective disorder
- Pervasive developmental disorders
- Current substance or alcohol dependence
- Neurological disorders
Key Trial Info
Start Date :
January 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2013
Estimated Enrollment :
129 Patients enrolled
Trial Details
Trial ID
NCT01907282
Start Date
January 1 2010
End Date
January 1 2013
Last Update
July 24 2013
Active Locations (8)
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1
UCLA School of Medicine
Los Angeles, California, United States, 90025
2
University of California, San Diego
San Diego, California, United States, 92093
3
Yale University
New Haven, Connecticut, United States, 06519
4
Emory University
Atlanta, Georgia, United States, 30322