Status:
COMPLETED
Induction of Immunity Against Streptococcus Pneumoniae in Adults With Inflammatory Bowel Disease
Lead Sponsor:
Klara M. Pósfay Barbe
Collaborating Sponsors:
Swiss IBD Cohort Study
Conditions:
Inflammatory Bowel Diseases
Crohn Disease
Eligibility:
All Genders
18-99 years
Phase:
PHASE4
Brief Summary
Patients with inflammatory bowel disease are at increased risk for infections due to their baseline disease and the subsequent immunocompromising regimen. Streptococcus pneumoniae (pneumococcus) has a...
Detailed Description
A. Inclusion: Patients are eligible for this study if they are part of the SIBDCS and are followed in Switzerland in Geneva, Vaud, Neuchatel or Bern. Gastroenterologist will present the study to the ...
Eligibility Criteria
Inclusion
- Being part of the Swiss IBD Cohort Study
- Being followed in Geneva, Neuchatel, Vaud or Bern
- Adult \>18 years-old
- informed consent form signed
- acceptance of PCV13 immunization
Exclusion
- Current relapse defined as a Crohn's Disease Activity Index (CDAI) \>150 for patients with Crohn's disease or a Modified Truelove-Witts Activity Index (MTWAI) \>10 for patients with ulcerative colitis
- Actually pregnant or planned pregnancy in the next month
- Immunization with a pneumococcal vaccine (conjugated or polysaccharide) in the previous 5 years
- Previous severe systemic reaction to immunization (respiratory or circulative)
- Episode of fever in the last 24 hours
Key Trial Info
Start Date :
March 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2016
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT01908283
Start Date
March 1 2014
End Date
December 1 2016
Last Update
September 18 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Hospitals of Geneva
Geneva, Switzerland, 1211