Status:
COMPLETED
Immune Response in Celiac Disease on In-vitro Gluten Challenge
Lead Sponsor:
Beth Israel Deaconess Medical Center
Conditions:
Celiac Disease
Eligibility:
All Genders
18-75 years
Brief Summary
The main purpose of this study is to see how cells taken from the lining of the intestine behave in the laboratory with exposure to gluten and other substances that act on the immune system. The cells...
Detailed Description
The primary purpose of this study is to determine the effect of in-vitro introduction of gluten on inflammatory response primarily Interferon-γ and other cytokines, such as IL-15, IL-18 and IL-21, in ...
Eligibility Criteria
Inclusion
- 18-75 years of age
- Undergoing a clinically indicated upper endoscopy
Exclusion
- Anticoagulation or antiplatelet therapy
- Known active non-celiac intestinal inflammatory disorder
Key Trial Info
Start Date :
February 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2018
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT01909050
Start Date
February 1 2013
End Date
March 1 2018
Last Update
March 19 2018
Active Locations (1)
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1
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States, 02215