Status:
COMPLETED
Study of the Effects of Negative Emotions on Endothelial Function
Lead Sponsor:
Columbia University
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Emotions
Endothelial Dysfunction
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Study aims and hypotheses are as follows: Primary Hypotheses: Compared to the neutral condition, the anger recall task will acutely induce endothelial dysfunction by impairing endothelium-dependent ...
Detailed Description
Atherosclerosis-related cardiovascular disease (CVD) events remain the leading causes of morbidity and mortality in industrialized nations. Atherosclerosis is a diffuse disease characterized by the de...
Eligibility Criteria
Inclusion
- Age 18 and over
- Fluent in English
Exclusion
- History of any chronic medical condition including prevalent CVD and traditional risk factors
- Active smoking
- Chronic medication use, including over-the-counter drugs or herbal medications
- History of psychosis, a mood disorder, or any overt personality disorder
- Latex allergy
- Poor peripheral veins with low possibility of getting IV access
Key Trial Info
Start Date :
September 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2020
Estimated Enrollment :
280 Patients enrolled
Trial Details
Trial ID
NCT01909895
Start Date
September 1 2013
End Date
November 1 2020
Last Update
January 27 2022
Active Locations (1)
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1
Columbia University Medical Center
New York, New York, United States, 10032