Status:
COMPLETED
Release of Osteogenic Markers in Immediately and Non-loaded Dental Implants
Lead Sponsor:
Renato Correa Viana Casarin
Conditions:
Jaw, Edentulous
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The aim of this study was to compare the release of the osteoprotegerin (OPG), transforming growth factors (TGF-α), osteocalcin (OCN), osteopontin (OPN), and parathyroid hormone (PTH) during osseointe...
Detailed Description
This was a prospective, parallel and controlled clinical-laboratory trial. The population evaluated in this study was selected at the Graduate Clinic in Dental Implantology - UNIP-SP. The selected pa...
Eligibility Criteria
Inclusion
- patients with mandibular and/or maxillary edentulous arch indicated for rehabilitation with dental implants
- extractions had to occur at least 4 months prior to treatment
- good oral hygiene (plaque index \< 20%) (Ainamo \& Bay, 1975)
- age between 18-65 years
Exclusion
- presence of systemic disease (including diabetes, arthritis, hypothyroidism, osteoporosis, etc) or use of medication (six months prior to the study) that contraindicated placement or alter implants osseointegration
- use of anti-inflammatory three months before surgery
- patients submitted to bone grafts in the site selected for the implant
- pregnant or breastfeeding women
- smokers or ex-smokers
Key Trial Info
Start Date :
March 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT01909999
Start Date
March 1 2010
End Date
December 1 2012
Last Update
July 29 2013
Active Locations (1)
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1
Faculty of Dentistry - Paulista University
São Paulo, São Paulo, Brazil, 04026-002