Status:

COMPLETED

Study to Assess the Safety and Bioeffect of REGN1033 (SAR391786)

Lead Sponsor:

Regeneron Pharmaceuticals

Collaborating Sponsors:

Sanofi

Conditions:

Healthy Volunteers

Eligibility:

All Genders

60+ years

Phase:

PHASE1

Brief Summary

This is a study to assess the safety and bioeffect of REGN1033 (SAR391786) in healthy volunteers.

Eligibility Criteria

Inclusion

  • Males and postmenopausal females aged 60 years and older with no significant health issues or clinically significant abnormal laboratory values.
  • Low activity lifestyle
  • Diet and exercise adherence

Exclusion

  • Significant concomitant illness such as, but not limited to cardiac, renal, rheumatologic, gastrointestinal, hematological, skeletal/muscular, neurologic, psychiatric, endocrine, metabolic or immunological disease.
  • Participation in any clinical trial within 6 months prior to screening.
  • Hospitalization, immobilization, or major surgical procedure requiring general anesthesia within 6 months prior to screening, or any planned surgical procedures during the study period.
  • Limb amputation (except for toes) and/or any fracture within 6 months.
  • The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial and not all inclusion/ exclusion criteria are listed.

Key Trial Info

Start Date :

August 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2014

Estimated Enrollment :

125 Patients enrolled

Trial Details

Trial ID

NCT01910220

Start Date

August 1 2013

End Date

October 1 2014

Last Update

November 10 2014

Active Locations (5)

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Page 1 of 2 (5 locations)

1

Gainesville, Florida, United States

2

Orlando, Florida, United States

3

Boston, Massachusetts, United States

4

St Louis, Missouri, United States