Status:
COMPLETED
Comparison of Two Strategies to Realize Apnea Test for the Diagnostic of Brain in Potentiel Organ Donors.
Lead Sponsor:
Poitiers University Hospital
Conditions:
Alternative Method of Apnea Test
Eligibility:
All Genders
18-75 years
Brief Summary
Clinical diagnostic of brain death requires a non-reactive coma, absence of brain stem reflex, and absence of spontaneous breathing. The confirmation of absence of spontaneous breathing is established...
Eligibility Criteria
Inclusion
- Age : from 18 to 75 years
- Neurological signs evoking cerebral ischemia
Exclusion
- Severe hypoxemia (PaO2/FiO2 \< 200) with controlled ventilation (FiO2: 100%)
- Hypothermia \< 36°C
- Obesity (BMI ≥ 40) with documented hypopnoea
- Intractable hypotension despite optimal filling and catecholamine doses \> 1µg.Kg.min
- Patients with contraindication for organs harvesting.
- Documented chronic respiratory failure
- Progressive infectious acute respiratory disease
- Family opposition to subject's participation in the study
Key Trial Info
Start Date :
July 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
208 Patients enrolled
Trial Details
Trial ID
NCT01911286
Start Date
July 1 2013
Last Update
October 11 2016
Active Locations (17)
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1
Angers University Hospital
Angers, France, 49933
2
Angoulême Hospital
Angoulême, France, 16959
3
Bordeaux University Hospital
Bordeaux, France, 33076
4
Brest University Hospital
Brest, France, 29200