Status:
COMPLETED
Diagnostic Value of 18F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Prosthetic Valve Endocarditis
Lead Sponsor:
Assistance Publique Hopitaux De Marseille
Conditions:
Prosthetic Valve Endocarditis (PVE)
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The diagnosis of prosthetic valve endocarditis (PVE) remains challenging. In PVE cases, initial echocardiography is normal or inconclusive in almost 30% of cases, leading to a decreased diagnostic acc...
Eligibility Criteria
Inclusion
- unexplained persistent or recurrent fever \>38°C;
- and/or unexplained increased serum C-reactive protein (CRP) level \>10 mg/L; and/or positive blood cultures, independent of the echocardiographic analysis results;
- and/or positive serological testing for Coxiella burnetii, Bartonella spp., Mycoplasma pneumoniae, Legionella pneumophila, Aspergillus spp., or Tropheryma whipplei;
- and/or a mass or a new partial prosthetic valve dehiscence observed using echocardiography.
Exclusion
- pregnancy,
- an inability to lie flat,
- a need for urgent cardiac surgery,
- hemodynamic instability,
- cardiac surgery \<1 month ago,
- and a blood glucose level \>1.8 g/L. Patients with a poor PET/CT image quality
Key Trial Info
Start Date :
February 5 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 21 2023
Estimated Enrollment :
174 Patients enrolled
Trial Details
Trial ID
NCT01916005
Start Date
February 5 2014
End Date
April 21 2023
Last Update
April 24 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Assistance Publique Hopitaux de Marseille
Marseille, France, 13354