Status:
ACTIVE_NOT_RECRUITING
Randomized Controlled Trial to Assess Blockade of Voltage Gated Sodium Channels During Surgery in Operable Breast Cancer
Lead Sponsor:
Tata Memorial Hospital
Collaborating Sponsors:
Shri Siddhivinayak Ganpati Cancer Hospital
Kolhapur Cancer Centre (KCC)
Conditions:
Operable Breast Cancer
Eligibility:
FEMALE
18-99 years
Phase:
PHASE3
Brief Summary
Voltage Gated Sodium Channels Over the years, there is more evidence that ionic channels are involved in the oncogenic process. Among these, voltage gated sodium channels (VGSC) expressed in non-nervo...
Eligibility Criteria
Inclusion
- All women with operable breast cancer planned for upfront surgery
- Histologically proven or clinically suspicious breast cancer
Exclusion
- Previous history of lumpectomy or incision biopsy
- Distant metastases
- Neoadjuvant Chemotherapy
- History of allergy to drugs (lignocaine)
- High risk factors precluding the use of lignocaine
- Previous history of cancer
Key Trial Info
Start Date :
December 12 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2026
Estimated Enrollment :
1600 Patients enrolled
Trial Details
Trial ID
NCT01916317
Start Date
December 12 2011
End Date
December 31 2026
Last Update
April 9 2025
Active Locations (11)
Enter a location and click search to find clinical trials sorted by distance.
1
Dr. B Barooha Cancer Institute
Guwahati, Assam, India, 781016
2
Gujarat Cancer & Research Institute (GCRI)
Ahmedabad, Gujarat, India, 380 016
3
Malabar Cancer Centre
Kannur, Kerala, India, 670103
4
Kolhapur Cancer Centre PVT LTD
Kolhāpur, Maharashtra, India, 416008