Status:
COMPLETED
Comparison of Treximet & Imitrex as They Affect the Levels of Inflammatory Markers When the Patient is Actively Having a Migraine Headache
Lead Sponsor:
Gary E. Ruoff, M.D.
Collaborating Sponsors:
GlaxoSmithKline
Conditions:
Migraine
Eligibility:
All Genders
18-65 years
Brief Summary
The primary objective is to determine whether inflammatory markers, such as C-Reactive Protein (CRP), Calcitonin Gene-Related Peptide (CGRP), Vasoactive Intestinal Polypeptide (VIP), or Substance P (S...
Detailed Description
Migraine is a neurovascular process involving the brain and related structures. Neuroinflammatory substances such as CRP, CGRP, VIP, SP, and prostaglandins are liberated during the migraine. Elevation...
Eligibility Criteria
Inclusion
- Subject must sign an informed consent
- Males and females 18 - 65 years of age
- Have episodic migraine headaches
- Patients to satisfy the diagnosis of migraine headaches with aura, without aura or mixed
- Must be able to differentiate migraine headaches from other headaches
- Diagnosis of migraines for at least 6 months
Exclusion
- Any medical condition, in the opinion of the investigator, that would make the subject unsuitable for enrollment
- Basilar or hemiplegic migraine headaches
- Pregnant woman or a nursing mother
- History (within 1 year) or current evidence of grug or alcohol abuse
- More than 15 migraine headaches per month
- Chronic daily headache
- Chronic use of NonSteroidalAntiInglammatoryDrugs
- Current participation in a research study or within the last 30 days
Key Trial Info
Start Date :
December 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2011
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01916395
Start Date
December 1 2009
End Date
July 1 2011
Last Update
August 5 2013
Active Locations (1)
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1
Westside Family Medical Center, PC
Kalamazoo, Michigan, United States, 49009