Status:
COMPLETED
The Effects of Enzymes and Flavonoids on Inflammation and Coagulation After Marathon
Lead Sponsor:
Technical University of Munich
Conditions:
Inflammation
Death, Sudden, Cardiac
Eligibility:
MALE
20-65 years
Phase:
PHASE1
Brief Summary
The aim of the present study is to investigate changes in inflammatory status and incidence of infection after extreme aerobic physical stress (participation in a marathon). In addition, the impact of...
Detailed Description
The influence of extreme physical stress, such as that experienced during marathon competition, on the inflammatory system and coagulation has been investigated. However, up until now, countermeasures...
Eligibility Criteria
Inclusion
- • Healthy male
- Age 20-65 years
- History of at least one successfully finished half marathon
- Intention to participate at the Munich Marathon 2013
- Subject is able to read, understand, and sign a written Informed Consent to participate in the Enzy-MagIC-Study
Exclusion
- Known cardiac disease
- Known allergy against the active ingredient of the study medication or pineapple, papaya, or kiwi
- Known severe coagulopathy
- Known lactose intolerance
- Pharmaceutical treatment for diabetes mellitus or arterial hypertension
- Acute or chronic renal failure
- Acute or chronic liver disease
- Acute or chronic infection or inflammatory disease
- Use of medications or supplements influencing immune function
- Musculoskeletal or psychiatric disease
- Neoplasia
- Participation in other interventional trials
Key Trial Info
Start Date :
August 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2014
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT01916408
Start Date
August 1 2013
End Date
August 1 2014
Last Update
June 30 2015
Active Locations (1)
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1
Department of Preventive and Rehabilitative Sports Medicine
Munich, Bavaria, Germany, 80992