Status:
COMPLETED
Farmed Fish Human Intervention Study
Lead Sponsor:
University of Aberdeen
Conditions:
Cardiovascular Disease
Eligibility:
All Genders
35-75 years
Phase:
NA
Brief Summary
Consumption of fish can help to prevent cardiovascular disease. The precise way in which fish is beneficial is not fully understood. This is important to find out as fish consists of a complex mixture...
Detailed Description
Aquaculture has the potential to take the pressure off wild fish stocks whilst meeting the dietary needs of the population for omega 3 fatty acids and other key nutrients such as vitamin D. The indust...
Eligibility Criteria
Inclusion
- Inclusion criteria: Healthy men and women aged 35-75 years BMI ranging from 18-35 kg/m2 Blood pressure below 160/90 mmHg; Total cholesterol \< 8.00 mmol/L Total/HDL cholesterol \< 6 mmol/L Fasting plasma glucose , 7 mmol/L Having a 10-20% risk for developing cardiovascular disease within the next 10 years based on the ASSIGN calculation (http://cvrisk.mvm.ed.ac.uk/index.htm) including the following factors: age, gender, number of cigarettes smoked per day, Scottish Index of Multiple Deprivation (SIMD)/postcode, systolic blood pressure, levels of total and HDL cholesterol and family history of cardiovascular disease, or having at least one additional risk factor such as being over 50 years old, BMI above 25 kg/m2, elevated triglyceride levels (\> 1.7 mmol/L) or elevated glucose levels (\> 5.6 mmol/L); platelet count \> 1709/L haematocrit above 40 % for males and above 35 % for females haemoglobin above 130 g/L for males and above 115 g/L for females
- Exclusion criteria Regularly taking aspirin or aspirin-containing drugs, or other anti-inflammatory drugs; Taking drugs or herbal medicines known to alter the haemostatic system in general; Taking any medicine known to affect lipid metabolism; Taking certain dietary supplements/multivitamin tablets; Diagnosis of diabetes, hypertension, renal, hepatic, haematological disease or coronary heart disease; Unsuitable veins for blood sampling; Inability to understand the participant information sheet; inability to speak, read and understand the English language.
Exclusion
Key Trial Info
Start Date :
March 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2016
Estimated Enrollment :
51 Patients enrolled
Trial Details
Trial ID
NCT01916434
Start Date
March 1 2013
End Date
March 1 2016
Last Update
March 25 2016
Active Locations (1)
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1
Rowett Institute of Nutrition and Health, Human Nutrition Unit
Aberdeen, United Kingdom, AB21 9SB