Status:
WITHDRAWN
Platelet-Rich Plasma vs Corticosteroid Injection as Treatment for Degenerative Pathology of the Temporomandibular Joint
Lead Sponsor:
Kaiser Permanente
Conditions:
Degenerative Joint Disease
Eligibility:
All Genders
Phase:
PHASE1
Brief Summary
1.0 BACKGROUND AND HYPOTHESES 1.1 Osteoarthritis is a continuous and entirely physiologic adaptive process that occurs in every joint. These include the replication of cells that produce matrix, enzy...
Detailed Description
2.0 OBJECTIVES AND PURPOSE 2.1 The purpose of this study is to compare the efficacy, in terms of pain relief and improvement in function, of intra-articular injections with platelet rich plasma versu...
Eligibility Criteria
Inclusion
- The following diagnostic criteria for patient selection are to be used:
- Patients will need to have a history of chronic pain (at least 3 months) refractory to conservative therapy with non-steroidal anti-inflammatory medications, muscle relaxants, diet modifications and splint therapy
- Patients will also need to have imaging findings (radiography or magnetic resonance imaging) that show mild to severe degenerative changes of the temporomandibular joint
Exclusion
- Exclusion criteria will include
- Patients with systemic disorders such as rheumatic diseases, hematologic diseases, active infections, immunosuppression
- Patients receiving therapy with anticoagulants
Key Trial Info
Start Date :
November 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT01920373
Start Date
November 1 2013
Last Update
March 11 2015
Active Locations (1)
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1
Kaiser Permanente Los Angeles Medical Center
Los Angeles, California, United States, 90027