Status:
COMPLETED
Effect of Perioperative Clopidogrel Responsiveness on Ischemic Outcome in Patients With Acute Coronary Syndrome Undergoing Off-pump Coronary Artery Bypass Surgery
Lead Sponsor:
Yonsei University
Conditions:
Acute Coronary Syndrome (ACS)
Eligibility:
All Genders
20-90 years
Brief Summary
The whole blood Thrombelastograph (TEG®) Platelet Mapping™ assay measures clot strength, maximal amplitude (MA), reflecting maximal platelet function, and detects the reduction in platelet function, p...
Eligibility Criteria
Inclusion
- the patients with ACS undergoing OPCAB
- the patients over 20 years of age
- the patient who have been taking \[100 mg of Aspirin\] and \[75 mg of clopidogrel or 180 mg of ticagrelor\] for more than one week and who continue within 3 to 5 days prior to surgery
Exclusion
- re-operation or emergency operation
- the patients with bleeding tendency of decreased liver function
- Left ventricular ejection fraction \< 40% by echo
- preoperative hematocrit \< 33% or platelet count \< 100,000/mm3 or creatinine \> 1.4 mg/dL
- abnormal preoperative prothrombin time or activated partial thromboplastin time
- preoperative use of other PO antiplatelet drugs or PO anticoagulants
Key Trial Info
Start Date :
July 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 30 2020
Estimated Enrollment :
195 Patients enrolled
Trial Details
Trial ID
NCT02184884
Start Date
July 1 2014
End Date
March 30 2020
Last Update
May 29 2020
Active Locations (1)
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1
Department of Anesthesiology and Pain Medicine
Seoul, South Korea, 120-752