Status:
COMPLETED
Measuring Collaterals With Multi-phase CT Angiography in Patients With Ischemic Stroke
Lead Sponsor:
Carol Kenney
Conditions:
Ischemic Stroke
Eligibility:
All Genders
18+ years
Brief Summary
Treatment of acute ischemic stroke (AIS) is aimed at salvaging viable but ischemic brain by opening the occluded artery and restoring anterograde perfusion as quickly as possible. Time saved while mak...
Eligibility Criteria
Inclusion
- Patient presenting to the emergency department with symptoms consistent with ischemic stroke.
- Age \> 18 yrs.
- Baseline imaging including multi-phase CTA done within 12 hours of stroke symptom onset and initiated before recanalization therapy.
- Evidence of a visible and symptomatic intracranial occlusion on baseline CT-angiography (intracranial ICA, M1 MCA segment +/- intracranial ICA, proximal M2 MCA).
- Treatment with IV tPA and/or IA therapy.
Exclusion
- Intracranial hemorrhage (ICH) identified on baseline CT.
- Previous moderate to large stroke in the ipsilesional hemisphere.
- Modified Rankin Scale \> 2 at baseline.
- Unable to have CT-angio performed due to recent estimated creatinine clearance eCCr\<60 ml/min, contrast allergy or other reasons.
- Participation in another study that results in the patient receiving an investigational drug or therapy.
- Any terminal illness (patient not expected to survive \> 1 year).
Key Trial Info
Start Date :
September 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2016
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT02184936
Start Date
September 1 2012
End Date
September 1 2016
Last Update
October 30 2017
Active Locations (2)
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1
Foothills Medical Centre
Calgary, Alberta, Canada, T2N 2T9
2
Arcispedale Sant'Anna · Department of Neurology
Ferrara, Italy