Status:
WITHDRAWN
Probiotic Use in Patients With Prior COPD Exacerbation
Lead Sponsor:
University of Oklahoma
Conditions:
COPD
Obstructive Lung Disease
Eligibility:
All Genders
18-99 years
Phase:
NA
Brief Summary
The purpose of the study is to examine the hypothesis test that probiotics will reduce the frequency of exacerbation in patients with COPD.
Eligibility Criteria
Inclusion
- Patients admitted to OUMC or VAMC with a COPD exacerbation and pneumonia with underlying COPD will be eligible and screened.
- Patients seen in VA Chest Medicine clinic, OU Physicians clinic and Pulmonary fellows clinic at PPOB who have had a COPD exacerbation within the last year.
- Patients over age 18
- Patients who have a pulmonary function test (PFT) showing COPD within 1 year of enrollment in the study or if the treating physician plans to obtain PFT as part of the patient's care plan.
- Patients will be considered to have a diagnosis of COPD if they have a FEV1 of less than 80% of predicted and a FVC/FEV1 ratio of less than 0.70 (as defined by GOLD criteria).
Exclusion
- Patients with less than one year of life expectancy from a concomitant diagnosis
- Any GI motility disorders or previous bowel resection surgery (short gut syndrome)
- Any patients with decreased immune function or on medication that may decrease immune function (other than low dose steroid or steroid taper).
- Patients admitted within the last one year with a diagnosis of pancreatitis
- Patients unable to give consent will not be included in the study.
- Patients unable to sign consent
- Patients already on azithromycin daily for COPD exacerbations
- Patients under department of corrections custody.
Key Trial Info
Start Date :
October 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2016
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT02185092
Start Date
October 1 2014
End Date
December 1 2016
Last Update
May 23 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
OUHSC
Oklahoma City, Oklahoma, United States, 73104