Status:
UNKNOWN
Effects of Subanesthetic Isoflurane/Sevoflurane in 60% Oxygen on Clinical In-vitro Experimental Sepsis
Lead Sponsor:
Air Force Military Medical University, China
Conditions:
Sepsis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Sepsis is a major cause of death in intensive care units. Despite the investigators improved understanding, which has reduced the risk of dying with sepsis, the number of people who die each year cont...
Detailed Description
100% oxygen or 0.5 MAC isoflurane/sevoflurane in 60% oxygen would inhibit increases of tumor necrosis factor (TNF)-alpha, interleukin-1beta, interleukin-6 in the cell culture supernatant after stimula...
Eligibility Criteria
Inclusion
- Human PBMCs were only isolated from the adult patients without sepsis/SIRS/infectious diseases.
- The plasma for induction of clinical in-vitro sepsis, was only isolated from adult patients with sepsis.
Exclusion
- Patients who had been selected for other clinical trials in the 3 months before.
Key Trial Info
Start Date :
June 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2018
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT02185118
Start Date
June 1 2014
End Date
July 1 2018
Last Update
July 9 2014
Active Locations (1)
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1
Department of Anesthesiology, Xijing Hospital, Fourth Military Medical University,
Xi'an, Shaanxi, China, 710032