Status:
COMPLETED
Effects of Dexmedetomidine on Respiratory Mechanics and Oxygenation During One Lung Ventilation With Chronic Obstructive Lung Disease
Lead Sponsor:
Yonsei University
Conditions:
COPD, One Lung Ventilation
Eligibility:
All Genders
40-80 years
Phase:
NA
Brief Summary
COPD is often associated with the airflow limitation and the pulmonary hyperinflation. During the one-lung ventilation (OLV), COPD patients' physiologic dead space increases and hypercapnia may develo...
Eligibility Criteria
Inclusion
- Above 40 years of age
- American Society of Anesthesiologists (ASA) Physical Status I, II, III.
- COPD diagnosed , criteria ( on preop. PFT : FEV1 \< 80%, FEV1 / FVC \< 70% after bronchodilator)
- thoracic surgical procedure
Exclusion
- severe functional liver or kidney disease
- diagnosed HF ( NYHA class \>3)
- arrhythmia or received treatment with antiarrythmic drug .
- exceed BMI \> 30 kg/ m2
- bradycardia (HR \<50 bpm)
Key Trial Info
Start Date :
July 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2015
Estimated Enrollment :
63 Patients enrolled
Trial Details
Trial ID
NCT02185430
Start Date
July 1 2014
End Date
April 1 2015
Last Update
October 14 2015
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