Status:

WITHDRAWN

Effects of Levothyroxine Treatment on Hemodynamic and Renal Functions in Subclinical Hypothyroidism

Lead Sponsor:

Centre Hospitalier Universitaire de Nice

Conditions:

Subclinical hypothyroïdism

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

Renal and cardiovascular effects of subclinical hypothyroidism, defined by a high TSH and normal T4 are less known and the indications for treatment of subclinical hypothyroidism are subject to contro...

Detailed Description

Animal experimental hypothyroidism is associated with renal and hemodynamic abnormalities. In human, exact measurements of GFR showed a decline in GFR after thyroidectomy and an increase in GFR and re...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • over 18 years
  • chronic kidney disease
  • subclinical hypothyroidism
  • non-inclusion Criteria:
  • insulin-dependent diabetes
  • dialysis

Exclusion

    Key Trial Info

    Start Date :

    October 1 2015

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    June 1 2017

    Estimated Enrollment :

    Patients enrolled

    Trial Details

    Trial ID

    NCT02186405

    Start Date

    October 1 2015

    End Date

    June 1 2017

    Last Update

    October 28 2016

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Nephrology Department

    Nice, France, 06202