Status:

COMPLETED

Ambulatory Post-Syncope Arrhythmia Protection Feasibility Study

Lead Sponsor:

Zoll Medical Corporation

Conditions:

Syncope

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to conduct an observational investigation of a novel care path used to manage emergency department (ED) presenting syncope patients on an outpatient basis.

Detailed Description

OBJECTIVES To conduct a prospective observational study assessing a unique outpatient care model in which syncope patients are provided with, and trained to use, a wearable defibrillator prior to disc...

Eligibility Criteria

Inclusion

  • Age≥18
  • Experienced a syncopal event within the past 48 hours
  • Either one of the following profiles(A or B) apply:
  • A. ED workup indicates that the patient may have experienced syncope that is cardiac in nature (any one or more of the following apply:
  • History or diagnosis of structural heart disease
  • History of cardiovascular disease
  • Age ≥ 40
  • Palpitations experienced pre-syncope
  • Major ECG abnormalities:
  • QRS-duration greater than 140 ms
  • PR-interval greater than 200 ms
  • Non-specific repolarization abnormality
  • Syncope experienced without any warning
  • Syncope experienced while supine
  • Syncope during exercise B. ED workup does not indicate a clear cause of the syncopal event

Exclusion

  • Clear diagnosis of non-cardiac syncope (e.g. orthostatic hypotensive syncope, vasovagal syncope, carotid sinus syncope, situational fainting)
  • An active implantable cardioverter-defibrillator (ICD)
  • An active unipolar pacemaker
  • Significant risk or suffering a cardiovascular event such as:
  • Symptoms of New York Heart Association (NYHA) class III or IV heart failure
  • ED diagnosis of acute coronary syndrome
  • Having required resuscitation in response to the index syncopal event
  • Advanced directive prohibiting resuscitation (DNR)
  • 6\. Physical or mental conditions preventing subjects from interacting with or wearing the device as determined by the investigating physician.
  • 7\. Bandages or other clinical condition preventing SWD 1000 use 8. Injuries or other conditions beyond simple syncope that require hospitalization 9. Travel out of town during the study participation period that prevents the field service representative from visiting the subject daily 10. Unable or unwilling to provide written informed consent

Key Trial Info

Start Date :

August 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 15 2020

Estimated Enrollment :

39 Patients enrolled

Trial Details

Trial ID

NCT02188147

Start Date

August 1 2014

End Date

April 15 2020

Last Update

February 21 2023

Active Locations (6)

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Page 1 of 2 (6 locations)

1

Danbury, Connecticut, United States

2

Jacksonville, Florida, United States

3

Minneapolis, Minnesota, United States

4

Saint Paul, Minnesota, United States