Status:
COMPLETED
Effect of Oral Health Ingredients on the Acquired Salivary Pellicle
Lead Sponsor:
Quadram Institute Bioscience
Collaborating Sponsors:
GlaxoSmithKline
Conditions:
Healthy
Eligibility:
All Genders
18-65 years
Brief Summary
The aim of this study is to help us understand how saliva forms a thin film inside the surfaces of the mouth which is known as the salivary pellicle, and how this film helps to protect our teeth from ...
Detailed Description
Saliva contains many proteins and components that contribute to film formation, and we know that saliva forms complex, structured films on surfaces. The mucosal salivary layer, comprises of a mobile l...
Eligibility Criteria
Inclusion
- Apparently Healthy
- Age: 18 - 65y
- Gender: Male or Female
- Non-smokers
- There are no restrictions regarding dietary habits
Exclusion
- have known diabetes
- have any medical history of Tuberculosis or Hepatitis
- have depressed or elevated blood pressure measurements (\<90/50 or \<95/50 if symptomatic or \>160/100).
- are currently undergoing any medical investigations
- have undergone any dental or mouth surgery, or tongue piercing within the last six weeks
- take any medication which may affect saliva production
- have any ongoing or chronic dental or mouth problems that may influence saliva composition
- have jaw or chewing problems which may be exacerbated by the saliva collection procedure
- are related to someone in the study team i.e. spouse, partner or immediate family member
- are pregnant, planning to become pregnant, or are currently breastfeeding.
- are not prepared to remove any tongue "piercings" prior to the saliva collection procedure.
- If results of the clinical screening which indicate, or are judged by the Human Nutrition Unit's (HNU) Medical Advisor to be indicative of, a health problem which compromise the well-being of the volunteer if they participated, or which would affect the study data.
Key Trial Info
Start Date :
July 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2018
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT02188238
Start Date
July 1 2014
End Date
December 31 2018
Last Update
March 7 2019
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Quadram Institute Bioscience
Norwich, Norfolk, United Kingdom, NR4 7UA