Status:

COMPLETED

Exercise Training to Lose Weight in Obese Asthmatics

Lead Sponsor:

University of Sao Paulo General Hospital

Collaborating Sponsors:

University of Sao Paulo

Fundação de Amparo à Pesquisa do Estado de São Paulo

Conditions:

Asthma

Obesity

Eligibility:

All Genders

30-60 years

Phase:

NA

Brief Summary

Obese asthmatics have more severe symptoms, reduced lung function, poorer quality of life and a reduced response to inhaled corticosteroid medication compared to non-obese asthmatics. In addition, the...

Detailed Description

This is a randomized, controlled and single blinded trial. Fifty-four asthmatic adults will be randomly assigned into two groups: DBG (dietary and behavioral support group) or DBE (similar to DBG + ex...

Eligibility Criteria

Inclusion

  • Asthma moderate and severe
  • Asthma will diagnosed (Global Initiative for Asthma -GINA)
  • Body Mass Index between 35 kg/ m2 and 39,9 kg/m2
  • Sedentary
  • Medical treatment, for at least 6 months
  • Clinically stable (i.e., no exacerbation or medication changes for at least 30 days)

Exclusion

  • Cardiovascular, musculoskeletal or other chronic lung diseases
  • Active Cancer
  • Pregnant
  • Weight loss more than 5 % in the preceding 6 months
  • Using weight-loss medications
  • History of bariatric surgery, uncontrolled hypertension or diabetes
  • Using overnight continuous positive airway pressure
  • Lactating
  • Current or ex-smoker

Key Trial Info

Start Date :

July 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2015

Estimated Enrollment :

55 Patients enrolled

Trial Details

Trial ID

NCT02188940

Start Date

July 1 2014

End Date

October 1 2015

Last Update

February 22 2016

Active Locations (1)

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Clinical Hospital of São Paulo University medical school (HCFMUSP)

São Paulo, São Paulo, Brazil, 05360-160