Status:
COMPLETED
Correlation Between Plasma- and Endothelial DPP-4 Activity
Lead Sponsor:
University Hospital, Gentofte, Copenhagen
Conditions:
Type 2 Diabetes Mellitus
Eligibility:
All Genders
35-80 years
Phase:
PHASE4
Brief Summary
The investigators want to estimate both the endothelial and the plasma activity of dipeptidyl peptidase 4 during different doses of sitagliptin in healthy subjects and patients with type 2 diabetes. F...
Detailed Description
The two incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are secreted from the intestinal L- and K- cells, respectively in response to ingestion...
Eligibility Criteria
Inclusion
- Caucasians with diet and/or metformin treated patients with type 2 diabetes (diagnosed according to the criterias of the World Health Organization)
- Normal Hemoglobin
- Prior Informed Consent
Exclusion
- Nephropathy
- Liver disease
- Inflammatory bowel disease
- Pregnancy
Key Trial Info
Start Date :
May 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2014
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT02192853
Start Date
May 1 2013
End Date
March 1 2014
Last Update
September 11 2017
Active Locations (1)
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1
Diabetes Research Division, Department of Endocrinology, Gentofte Hospital
Hellerup, Denmark, 2900