Status:
COMPLETED
Assessment of Cardiopulmonary Function in Duchenne Muscular Dystrophy
Lead Sponsor:
University of Florida
Collaborating Sponsors:
CureDuchenne
Conditions:
Muscular Dystrophy, Duchenne
Eligibility:
MALE
5-15 years
Brief Summary
This study seeks to develop and validate non-invasive assessments of cardiac and respiratory muscles with magnetic resonance imaging (MRI) to better predict the natural disease progression of Duchenne...
Detailed Description
Magnetic Resonance Imaging (MRI) of the heart and breathing muscles, special breathing tests (called pulmonary function testing), special exercise tests (using a stationary bike), and possibly an echo...
Eligibility Criteria
Inclusion
- Male
- 5-15 years old at the time of enrollment
- Diagnosed with DMD (as defined by parent project)
- Written parental informed consent (and assent where appropriate) before any study procedures take place
Exclusion
- Contraindication to an MRI examination
- Presence of a secondary condition that impacts muscle function or metabolism, that leads to developmental delay or impaired motor control, or that is not stable
- Participant is unable to comply with study requirements
- Congenital structural abnormality of the heart, repaired or unrepaired
- Clinically contraindicated participation
Key Trial Info
Start Date :
December 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 6 2019
Estimated Enrollment :
9 Patients enrolled
Trial Details
Trial ID
NCT02195999
Start Date
December 1 2013
End Date
March 6 2019
Last Update
July 8 2019
Active Locations (1)
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1
Clinical and Translational Research Building
Gainesville, Florida, United States, 32610