Status:
COMPLETED
The Selection Criteria for the Second-look Endoscopy Among Patients With Bleeding Peptic Ulcers
Lead Sponsor:
National Cheng-Kung University Hospital
Collaborating Sponsors:
National Science and Technology Council, Taiwan
Conditions:
Peptic Ulcer Hemorrhage
Eligibility:
All Genders
20-95 years
Brief Summary
The purpose of this prospective study is to identify risk factors which could predict poor fading of SRH or early recurrent bleeding of peptic ulcer hemorrhage after successful endoscopic hemostasis a...
Detailed Description
Peptic ulcer bleeding is a common disease, and recurrent bleeding is an independent risk factor leading to mortality. The appearance of stigmata of recent hemorrhage (SRH) indicates possible recurrenc...
Eligibility Criteria
Inclusion
- Bleeding peptic ulcers with major stigmata of recent hemorrhage
- All of these major SRH are treated by local injection of diluted epinephrine 1:10000 with or without combined therapy with a heater probe, argon plasma coagulation, band ligation, or hemoclip therapy
Exclusion
- Bleeding due to tumor or cancer
- Bleeding due to the presence of a Dieulafoy lesion
- Ulcer bleeding due to mechanical factors (i.e., gastrostomy tube induction)
- Proton pump inhibitors use within one week before enrollment
- Failure to establish hemostasis under gastroscopy
- Hypersensitivity to esomeprazole, pantoprazole, or any component of the formulation
- Previously participated in the study
Key Trial Info
Start Date :
August 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2014
Estimated Enrollment :
316 Patients enrolled
Trial Details
Trial ID
NCT02197039
Start Date
August 1 2011
End Date
July 1 2014
Last Update
July 26 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
National Cheng Kung University Hospital
Tainan, Taiwan, 704