Status:
UNKNOWN
Paradoxical Excitement Response During Sedation Between Dexmedetomidine and Propofol in Hazardous Alcohol Drinker
Lead Sponsor:
Chonnam National University Hospital
Conditions:
Anesthesia, Spinal
Sedation, Conscious
Eligibility:
All Genders
19-65 years
Phase:
PHASE4
Brief Summary
1. Adequate sedation with classical sedative agents, propofol 2. Sedation with propofol may induce paradoxical excitement response in heavy alcohol drinkers 3. Dexmedetomidine, α2 receptor agonist, ma...
Detailed Description
1. Adequate sedation during surgery provide anxiolysis and comfort to patient. Insufficient sedation can't provide comfort to patient during surgery, otherwise excessive sedation can cause variable co...
Eligibility Criteria
Inclusion
- 19\~65 yr-old patients who is scheduled to undergo knee surgery with regional anesthesia
Exclusion
- History of taking anxiolytics, hypnotics, antiepileptic drugs
- Abnormal liver function test (eg: Liver cirrhosis, elevated liver enzymes)
- History of allergic reaction with dexmedetomidine or propofol
- Contraindication with regional anesthesia
- American society of anesthesiologist Physical status III or IV
Key Trial Info
Start Date :
December 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 31 2019
Estimated Enrollment :
110 Patients enrolled
Trial Details
Trial ID
NCT02197403
Start Date
December 1 2013
End Date
May 31 2019
Last Update
March 14 2019
Active Locations (1)
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1
Chonnam National University Hwasun Hospital
Hwasun, Jeollanamdo, South Korea, 501-757