Status:

COMPLETED

Genetic Variants and Iron Absorption

Lead Sponsor:

Cornell University

Conditions:

Iron Absorption

Eligibility:

FEMALE

18-35 years

Brief Summary

The two specific aims of this study are: 1) to assess the impact of a genetic variant on iron status; 2) to assess the impact of a genetic variant on non-heme absorption among Asian women. The investi...

Detailed Description

To determine the HFE genotype of female Asian study volunteers, we collected venous blood samples and extracted DNA from these blood samples. HFE genotype was determined as CC, CT, and TT and used to ...

Eligibility Criteria

Inclusion

  • non-pregnant and between the ages of 18\~35 y
  • East Asian descent with both maternal and paternal grandparents from East Asia, including China, Japan, South Korea, Vietnam, Thailand, Malaysia and Singapore

Exclusion

  • taking or planing to take any vitamin or mineral supplements during the study period
  • pre-existing medical problems that might impact inflammation or Fe status, including malabsorption, blood disorders, ulcers, joint diseases and asthma
  • taking any prescribed medications known to affect iron homeostasis

Key Trial Info

Start Date :

June 1 2012

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 1 2014

Estimated Enrollment :

57 Patients enrolled

Trial Details

Trial ID

NCT02197624

Start Date

June 1 2012

End Date

May 1 2014

Last Update

July 23 2014

Active Locations (1)

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1

Human Metabolic Research Unit, Cornell University

Ithaca, New York, United States, 14853