Status:

COMPLETED

Xience or Vision Stent Management of Angina in the Elderly

Lead Sponsor:

Brighton and Sussex University Hospitals NHS Trust

Collaborating Sponsors:

Abbott Medical Devices

Conditions:

Coronary Artery Disease

Eligibility:

All Genders

80+ years

Phase:

NA

Brief Summary

The treatment of complex coronary disease causing limiting symptoms of angina with drug-eluting stent technology will prove superior to bare metal stent technology, with respect to a combined endpoint...

Eligibility Criteria

Inclusion

  • AGE\>80
  • Stable angina or acute coronary syndrome
  • Coronary narrowing suitable for stenting that is either ≥15mm long and/or ≤3mm diameter.
  • Any lesion with high risk of restenosis eg chronic total occlusion, bifurcation, severe calcification
  • Any left main stem lesion

Exclusion

  • Acute ST segment elevation myocardial infarction
  • Cardiogenic shock
  • Platelet count =50 x 109/mm3
  • Patient life expectancy \< 1 year
  • Known allergies to clopidogrel, aspirin, heparin, stainless steel, IV contrast or stent drug elutant
  • Recent major GI haemorrhage (within 3 months)
  • Any previous cerebral bleeding episode
  • Participation in another investigational drug or device study
  • Patient unable to give consent
  • Clinical decision precluding the use of drug eluting stent

Key Trial Info

Start Date :

November 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2012

Estimated Enrollment :

800 Patients enrolled

Trial Details

Trial ID

NCT02198716

Start Date

November 1 2008

End Date

August 1 2012

Last Update

August 15 2014

Active Locations (1)

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1

Cardiac Research Unit

Brighton, Sussex, United Kingdom, BN2 1ES