Status:

TERMINATED

Phenylephrine Versus Norepinephrine for Septic Shock in Critically Ill Patients

Lead Sponsor:

Vanderbilt University Medical Center

Collaborating Sponsors:

National Center for Research Resources (NCRR)

National Center for Advancing Translational Sciences (NCATS)

Conditions:

Septic Shock

Sepsis

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

Septic shock is a condition that is marked by severe infection causing hypotension requiring vasopressors to maintain adequate perfusion to vital organs. The Surviving Sepsis campaign, an internationa...

Eligibility Criteria

Inclusion

  • Adults 18 years of age or greater
  • Intention to treat with vasopressor for diagnosis of septic shock
  • Exclusion criteria not met

Exclusion

  • Emergent indication for surgery
  • Patient possesses a terminal condition for which patient or medical decision maker has decided to de-escalate medical care (patients with Do Not Resuscitate order but for whom standard care is continued will not be excluded)
  • Known allergy to phenylephrine or norepinephrine
  • Treated with vasopressor \>12 hours for current episode of shock
  • Preference of specific vasopressor agent by patient's provider
  • Pregnancy

Key Trial Info

Start Date :

August 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2016

Estimated Enrollment :

17 Patients enrolled

Trial Details

Trial ID

NCT02203630

Start Date

August 1 2014

End Date

January 1 2016

Last Update

June 13 2018

Active Locations (1)

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Vanderbilt University Medical Center

Nashville, Tennessee, United States, 37232