Status:
COMPLETED
Trial of Naltrexone and Dextromethorphan for Gulf War Illness
Lead Sponsor:
East Carolina University
Conditions:
Gulf War Illness
Eligibility:
All Genders
18-100 years
Phase:
PHASE2
Brief Summary
Veterans of the 1991 Gulf War who developed Gulf War Illness are being studied. Treatments with FDA approved generic drugs are being administered to see if they help with the symptoms of Gulf War Illn...
Detailed Description
Gulf war veterans' illnesses comprise distinct clusters of symptom-defined illnesses for which there are neither diagnostic tests nor effective treatments. Gulf war veterans had variable exposures to ...
Eligibility Criteria
Inclusion
- Served in the Gulf War and developed the symptoms of Gulf War Illness as described by the modified Kansas Case Definition
Exclusion
- Pregnant women, nursing mothers, individuals requiring medications that have drug interactions with dextromethorphan or naltrexone, cancer not in remission, chronic infectious disease, liver disease, lupus, multiple sclerosis, stroke, under current treatment for schizophrenia, bipolar disorder/manic depression, and depression.
- Those with a history of current illicit drug use will be excluded. Individuals who have had recent surgery will not be enrolled until they have completely recovered from the surgery.
- Subjects participating in other clinical trials will be excluded.
- Those enrolled recently in a clinical trial will be enrolled after a washout period of one month.
Key Trial Info
Start Date :
January 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2016
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT02206490
Start Date
January 1 2012
End Date
January 1 2016
Last Update
March 3 2016
Active Locations (1)
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1
Brody School of Medicine a East Carolina Univesity
Greenville, North Carolina, United States, 27834