Status:
UNKNOWN
Ambulosono Rasagiline Musical Walking Study
Lead Sponsor:
University of British Columbia
Collaborating Sponsors:
Teva Branded Pharmaceutical Products R&D, Inc.
Conditions:
Parkinson's Disease
Eligibility:
All Genders
19+ years
Phase:
NA
Brief Summary
This study will investigate the effects of a contingency-based musical walking intervention program called Ambulosono on neural mechanisms in the brain. The investigators will investigate the long-ter...
Eligibility Criteria
Inclusion
- Over 19 years of age
- Confirmed diagnosis of Parkinson's Disease
- Can walk 5 to 10 minutes unassisted
- Have a safe place to walk (outdoor or indoor)
- Have mild to moderate Parkinson's disease (HY1-3)
- Be able to lay flat in the scanner for the period of the study
- No reliance on wheelchair or other walking aid for ambulation
- Absence of any other serious medical conditions such as hearing impairment and dementia
- No history of other neurological and psychiatric illnesses
- No recent musculoskeletal impairment or injuries that may prevent walking
Exclusion
- Under 19 years of age
- Unconfirmed PD diagnosis
- Require walking aid, wheelchair-bound
- No access to safe walking pathway
- Severe PD (Hoehn \& Yahr stages\>3)
- Impaired hearing
- Atypical Parkinsonism
- Concurrent dementia
- Recent knee, hip or foot injury (need permission from doctor)
- Exclusion Criteria for fMRI
- Pacemaker
- Brain aneurysm clip
- Cochlear implant
- Recent surgery within the past 6 weeks
- Possibility of pregnancy
- Electrical stimulator for nerves or bones
- Implanted infusion pump
- History of any eye injury involving metal fragments
- History of working with metals (grinding, machining, or welding)
- Artificial heart valve
- Orthopaedic hardware (artificial joint, plate, screws, rods)
- Other metallic prostheses
- Coil, catheter or filter in any blood vessel
- Ear or eye implant
- Recent tattoos within the past 6 weeks
- Shrapnel, bullets, or other metallic fragments
- Medication releasing skin patches (nicotine, birth control, nitroglycerine)
Key Trial Info
Start Date :
October 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2017
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT02207387
Start Date
October 1 2013
End Date
March 1 2017
Last Update
April 2 2015
Active Locations (1)
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1
Pacific Parkinson's Research Centre
Vancouver, British Columbia, Canada, V6P 2Z9