Status:

COMPLETED

Evaluating PCSK9 Binding antiBody Influence oN coGnitive HeAlth in High cardiovascUlar Risk Subjects

Lead Sponsor:

Amgen

Conditions:

Dyslipidemia

Eligibility:

All Genders

40-85 years

Phase:

PHASE3

Brief Summary

This study evaluated change over time in neurocognitive testing in patients receiving statin therapy in combination with evolocumab (AMG 145), compared with patients receiving statin therapy in combin...

Detailed Description

Participants who were enrolled in study 20110118 (FOURIER; NCT01764633) at select sites in select countries (selected based on study start-up timelines) were invited to participate in this cognitive f...

Eligibility Criteria

Inclusion

  • Randomized into Study 20110118 (FOURIER; NCT01764633)

Exclusion

  • Current or known past diagnosis of dementia or mild cognitive impairment (MCI)

Key Trial Info

Start Date :

September 10 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 11 2016

Estimated Enrollment :

1974 Patients enrolled

Trial Details

Trial ID

NCT02207634

Start Date

September 10 2014

End Date

November 11 2016

Last Update

January 16 2018

Active Locations (416)

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Page 1 of 104 (416 locations)

1

Research Site

Birmingham, Alabama, United States, 35294

2

Research Site

Huntsville, Alabama, United States, 35801

3

Research Site

Mobile, Alabama, United States, 36608

4

Research Site

Glendale, Arizona, United States, 85306