Status:

COMPLETED

Loteprednol Etabonate Ophthalmic Gel for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery

Lead Sponsor:

Bausch & Lomb Incorporated

Conditions:

Inflammation

Pain

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The objective of this study is to evaluate the safety and efficacy of loteprednol etabonate (LE) ophthalmic gel, 0.38% (BID)

Detailed Description

The objective of this study is to evaluate the safety and efficacy of loteprednol etabonate (LE) ophthalmic gel, 0.38% (BID) for the treatment of inflammation and pain following cataract surgery.

Eligibility Criteria

Inclusion

  • Visit 1 (Screening Visit)
  • Be willing and able to comply with all treatment and follow-up/study procedures.
  • Be a candidate for routine, uncomplicated cataract surgery.
  • Visit 3 (Postoperative Day 1)
  • Have undergone routine, uncomplicated cataract surgery (phaco-emulsification with posterior chamber intraocular lens (IOL) implantation, not combined with any other surgery) in the study eye.
  • Have ≥ Grade 2 anterior chamber (AC) cells (6-15 cells) in the study eye.

Exclusion

  • Have a severe/serious ocular condition or history/presence of chronic generalized systemic disease that the Investigator feels might increase the risk to the subject or confound the result(s) of the study.
  • Have known hypersensitivity or contraindication to the study drug(s) or their components.

Key Trial Info

Start Date :

September 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2015

Estimated Enrollment :

326 Patients enrolled

Trial Details

Trial ID

NCT02208297

Start Date

September 1 2014

End Date

March 1 2015

Last Update

September 25 2020

Active Locations (1)

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Bausch & Lomb Incorporated

Bridgewater, New Jersey, United States, 08807