Status:
COMPLETED
Effects of Low Dose Aspirin Pre-treatment on Platelet Activation Undergoing Off-pump Coronary Artery Bypass Surgery
Lead Sponsor:
Seoul National University Hospital
Conditions:
Coronary Artery Disease
Eligibility:
All Genders
20-80 years
Phase:
NA
Brief Summary
Platelet activation after off pump coronary artery bypass (OPCAB) surgery may affect thrombus formation. The purpose of this study is to assess the effects of preoperative continuation of aspirin on p...
Detailed Description
Patients undergoing OPCAB surgery will be randomized to continue preoperative aspirin or discontinue aspirin before surgery. Platelet activation can be evaluated by measuring platelet p-selectin usin...
Eligibility Criteria
Inclusion
- age : 20-80
- elective OPCAB
- informed consent
Exclusion
- coagulation disorder
- emergency operation, re-operation
- co-existing valvular disease
- less than 6 months after cerebral vascular accident
- heparin induced thrombocytopenia
- heparin resistance
- menstrual phase
- preoperative cardiopulmonary bypass, continuous veno-veno hemofiltration, intra-aortic balloon pump application
- less than 12 months after myocardiac infarction
- less than 10 days after unstable angina
- less than 30 days after percutaneous coronary intervention
- less than 6 wks after bare metal stent insertion
- less than 12 months after drug eluting stent insertion
Key Trial Info
Start Date :
July 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2015
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT02209909
Start Date
July 1 2014
End Date
September 1 2015
Last Update
April 21 2016
Active Locations (1)
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1
Seoul National University Hospital
Seoul, South Korea