Status:
COMPLETED
The Microvascular Brain Retina And Kidney Study
Lead Sponsor:
Fondation Ophtalmologique Adolphe de Rothschild
Collaborating Sponsors:
French National Agency for Research on AIDS and Viral Hepatitis
Conditions:
Cerebral Small Vessels Disease
Eligibility:
All Genders
50+ years
Brief Summary
Cerebral small vessel disease (CSVD) is a major cause of cognitive impairment and disability in the general population, secondary to the accumulation of asymptomatic elementary lesions. CSVD is direct...
Eligibility Criteria
Inclusion
- age over 50 years old
- chronic HIV seropositive patient infected for at least 5 years
- antiretroviral therapy
- plasmatic HIV viral load \<40 copies/ml for at least one year with one authorized blip \< 1000 copies/ml per year
- cerebral small vessels disease (patients) or not (controls)
Exclusion
- Co-infection VHC
- known antecedent of stroke
- documented neurologic complication of HIV
- drug user
- glomerular filtration rate\< 15 mL/mn
- diabetic patient with kidney or retin complications
- systolic blood pressure≥ 180 and/or diastolic blood pressure≥ 110 mmHg
Key Trial Info
Start Date :
May 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2017
Estimated Enrollment :
163 Patients enrolled
Trial Details
Trial ID
NCT02210130
Start Date
May 1 2014
End Date
April 1 2017
Last Update
August 9 2018
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Fondation Ophtalmologique Adolphe de Rothschild
Paris, Île-de-France Region, France, 75019