Status:
COMPLETED
Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy
Lead Sponsor:
Indiana University
Conditions:
Delirium
Cognitive Impairment
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to investigate the effectiveness of a preventative low-dose of Haloperidol to prevent delirium in patients undergoing a esophagectomy, pneumonectomy or thoracotomy. Delir...
Detailed Description
50% of patients who undergo esophageal and/or lung resection suffer from acute brain dysfunction or delirium postoperatively. Delirium is a state of brain failure characterized by disturbance of consc...
Eligibility Criteria
Inclusion
- At least ≥ 18 years of age and older
- Undergoing a possible or scheduled thoracotomy
- English speaking
Exclusion
- History of Schizophrenia and Parkinson's disease
- History of Severe Dementia
- History of Alcohol Abuse
- On Cholinesterase Inhibitors or Levodopa
- Pregnant or Nursing
- Corrected QT interval \> 550 milliseconds at the time of randomization
- History of Neuroleptic Malignant Syndrome or Haloperidol Allergy
Key Trial Info
Start Date :
September 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2015
Estimated Enrollment :
135 Patients enrolled
Trial Details
Trial ID
NCT02213900
Start Date
September 1 2013
End Date
December 1 2015
Last Update
April 13 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Hospital
Indianapolis, Indiana, United States, 46202