Status:
COMPLETED
Restrictive Fluid Therapy in Severe Preeclampsia
Lead Sponsor:
University of Sao Paulo General Hospital
Conditions:
Pre-Eclampsia
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
Introduction: Pre-eclampsia is a multifactorial syndrome which occurs in hypertension and proteinuria in pregnant women over 20 weeks gestation. It is the leading cause of maternal complications such ...
Detailed Description
Preeclampsia (PE) is the leading cause of morbidity and mortality worldwide during pregnancy. Fluid therapy for PE women during cesarean section is a controversial issue among medical specialists. Th...
Eligibility Criteria
Inclusion
- Severe PE was defined as at least one of the following criteria: systolic pressure ≥160 mmHg or diastolic pressure ≥110 mmHg, severe proteinuria (\>5 g/24 h), oliguria (\<500 ml/24 h), cerebral or visual disturbances, pulmonary edema, epigastric pain, hepatic rupture, impaired liver function, thrombocytopenia, hemolysis, elevated liver enzymes and low platelet count (HELLP) syndrome and evidence of fetal compromise.
Exclusion
- previous serum creatinine levels \>1 mg/dl
- previous kidney disease
- contraindication to spinal anesthesia
Key Trial Info
Start Date :
January 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2015
Estimated Enrollment :
46 Patients enrolled
Trial Details
Trial ID
NCT02214186
Start Date
January 1 2014
End Date
May 1 2015
Last Update
March 7 2017
Active Locations (1)
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1
Hospital das Clínicas da Faculdade de Medicina da USP
São Paulo, São Paulo, Brazil, 01246903